THE ROYAL INSTITUTION FOR THE ADVANCEMENT OF LEARNING / MCGILL UNIVERSITY
发明人:
Michel L. TREMBLAY,Claudia PENAFUERTE,Matthew FELDHAMMER,George ZOGOPOULOS,Cameron BLACK,Brian KENNEDY
申请号:
US15709688
公开号:
US20180072763A1
申请日:
2017.09.20
申请国别(地区):
US
年份:
2018
代理人:
摘要:
The invention encompasses the novel class of compounds represented by the Formula (I) below, which are inhibitors of the TC-PTP enzyme. The invention also encompasses pharmaceutical compositions which include the compounds shown above and methods of treating or preventing TC-PTP mediated diseases, including cancer, via their use in the activation of antigen-presenting cells, like dendritic cells, for applications in the immunotherapeutic treatment of diseases.