PROBLEM TO BE SOLVED: To provide an adsorbent that can efficiently adsorb and remove PCSK9 in body fluid, and to provide an adsorber.SOLUTION: The adsorbent 3 of the PCSK9 includes a water insoluble carrier having an anionic functional group. Moreover, the adsorber 7 of the PCSK9 is filled with the adsorbent 3 of the PCSK9 in a container with a liquid inlet 1 and a liquid outlet 2 and a flowout prevention means 5 for preventing the adsorbent 3 from flowing out the container.