Henrik Frydenlund Hansen,Jens Bo Rode Hansen,Christoph Rosenbohm,Ellen Marie Straarup
申请号：
US12532275
公开号：
US08470791B2
申请日:
2008.03.19
申请国别(地区):
US
年份:
2013
代理人:
摘要：
Short oligonucleotides directed against the Apo-B100 gene are provided for modulating the expression of Apo-B100. Methods of using these compounds for modulation of Apo-B100 expression and for the treatment of diseases associated with Apo-B100 expression are provided. The oligonucleotides comprise deoxyribonucleosides and locked nucleic acids.
