A medical guide wire which has a core wire (10) having a distal end-side small-diameter portion (11) and a proximal end-side large-diameter portion (14) and a coil spring (20) installed on an outer periphery of the distal end-side small-diameter portion (11) of the core wire (10) along an axial direction having a front end-side small-diameter portion (21) a tapered portion (22) and a rear end-side large-diameter portion (23) and fixed to the core wire (10) at at least the front end portion and rear end portion thereof wherein the length of the front end-side small-diameter portion(21)of the coil spring(20)is 5 to 100 mm and the outside diameter of coil thereof is at most 0.012 inch the front end portion of coil spring(20)is fixed to the core wire(10)by gold-containing solder and the length of a distal end portion stiffened by the gold-containing solder is 0.1to0.5 mm.