Antibodies against HMGB1 and fragments thereof

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专利权人:

Davorka Messmer

发明人:

Davorka Messmer

申请号：

US11922259

公开号：

US08354106B2

申请日:

2006.06.15

申请国别(地区):

US

年份:

2013

代理人:

摘要：

In various embodiments, the present invention is drawn to antibodies or antigen-binding fragments thereof that bind to particular fragments of HMGB1, methods of treating a condition in a subject characterized by activation of an inflammatory cytokine cascade, methods of detecting and/or identifying an agent that binds to an HMGB1 polypeptide or fragment thereof, and methods of detecting HMGB1 in a sample.

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