The present invention relates to novel compounds suitable e.g. as therapeutic agents for use in the treatment of mammalian disease and in particular to novel therapeutic agents suitable for use in the treatment of microbial infection in mammals. The present invention further relates to the use of pharmaceutical compositions comprising said agents in the treatment of medical conditions in mammals, in particular in the treatment of microbial infection. The agents and pharmaceutical compositions of the invention are of particular relevance in the treatment of diseases associated with antibiotic-resistant microbes. The present invention also relates to processes for making said agents.本發明係關於適用為例如用於治療哺乳類動物疾病之治療藥劑的新穎化合物,且尤其關於適用於治療哺乳類動物中微生物感染之新穎治療藥劑。本發明更關於使用包含該藥劑之醫藥組合物於在醫療情況下治療哺乳類動物之用途,尤其是於治療微生物感染之用途。本發明之藥劑及醫藥組合物於與具抗生素抗性之微生物相關之疾病的治療尤其具關連性。本發明亦關於製造該藥劑之製程。