An orthotopic artificial bladder endoprosthesis comprises a casing (2) made of a PGA fiber fabric said casing (2) having two first connectors (3) for the connection with the ureters of a patient and a second connector (4) for the connection with the urethra of a patient a support element (5) being inserted in said casing (2) said support element (5) being switchable between an extended configuration in which it supports and maintains in position the casing (2) and a retracted configuration.