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Composition containing glibenclamide
专利权人:
BIOGEN CHESAPEAKE LLC
发明人:
Sven Martin Jacobson,Robert Ang
申请号:
US16599327
公开号:
US10758503B2
申请日:
2019.10.11
申请国别(地区):
US
年份:
2020
代理人:
摘要:
NSC antagonists are disclosed as useful in the treatment of dementia, in delaying the onset of dementia, and in the prevention of dementia. Dementia so treated may be, for example, Alzheimer's Disease (AD). NSC antagonists for treating dementia such as AD may be administered alone, a) in combination with other drugs used for treating dementia, b) in combination with drugs that stabilize or increase blood plasma glucose levels, or with both a) and b). Pharmaceutical compositions, dosage forms, and methods for using the same are disclosed, which include NSC antagonists, NSC antagonists combined with dementia drugs, NSC antagonists combined with glucose-level stabilizing or enhancing drugs, or combinations of these. Dosage forms may be designed to provide stable plasma levels for extended periods of time. Exemplary pharmaceutical compositions include compositions including glibenclamide and memantine; glibenclamide and donepezil; tolbutamide and memantine; tolbutamide and donepezil; and these compositions further including glucagon and/or glucose.
来源网站:
中国工程科技知识中心
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http://www.ckcest.cn/home/

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