Michael D. Carter,Donald F. Weaver,Sheila Marie H. Jacobo,Erhu Lu,Fuye Gao
申请号:
US12312543
公开号:
US08362066B2
申请日:
2007.11.19
申请国别(地区):
US
年份:
2013
代理人:
摘要:
The invention is directed to compounds and methods for treating protein folder disorders. In certain embodiments the invention provides compounds and methods for treating neurodegenerative diseases such as Alzheimers disease, tauopathy, cerebral amyloid angiopathy, Lewy body disease, dementia, Huntingtons disease and prion-based spongiform encelopathy. The invention further provides compounds, methods and pharmaceutical compositions for inhibiting tau protein, Aβ protein or α-synuclein protein aggregation.