The present invention relates to specific doses of and dosing regimens forusing a 1,2,4-oxadiazole benzoic acid compound in treating or preventingdiseases associated with nonsense mutations. In particular, the inventionrelates to specific doses and dosing regimens for the use of 3-[5-(2-fluoro-phenyl)-[l,2,4]oxadiazol-3-yl]-benzoic acid in mammals having diseasesassociated with nonsense mutations.