DANMARKS TEKNISKE UNIVERSITET;STATENS SERUM INSTITUT
发明人:
JUNGERSEN, GREGERS,THAKUR, ANEESH,AAGAARD, CLAUS,ANDERSEN, PETER LAWAETZ,MIKKELSEN, HEIDI
申请号:
CA2898418
公开号:
CA2898418A1
申请日:
2014.01.28
申请国别(地区):
CA
年份:
2014
代理人:
摘要:
The present invention provides one or more immunogenic polypeptides for use in a preventive or therapeutic vaccine against latent or active infection in a human or animal caused by a Mycobacterium species, e.g. Mycobacterium avium subsp. paratuberculosis. Furthermore a single or multi-phase vaccine comprising the one or more immunogenic polypeptides is provided for administration for the prevention or treatment of infection with a Mycobacterium species, e.g. Mycobacterium avium subsp. paratuberculosis. Additionally, nucleic acid vaccines, capable of in vivo expression of the multi-phase vaccine comprising the one or more immunogenic polypeptides, is provided for prevention or treatment of infection with a Mycobacterium species, e.g. Mycobacterium avium subsp. paratuberculosis.