STEINHAGEN, HENNING,SCHEIPER, BODO,MATTER, HANS,STILZ, HANS ULRICH,MCCORT, GARY
申请号:
CA2712854
公开号:
CA2712854C
申请日:
2009.01.17
申请国别(地区):
CA
年份:
2016
代理人:
摘要:
The present invention relates to cyclic indole-3-carboxamides of the Formula(I), wherein A, R, R10, R20, R30, R40,n, p and q have the meanings indicated in the claims, which are valuablepharmaceutical active compounds. Specifically, they inhibitthe enzyme renin and modulate the activity of the renin-angiotensin system,and are useful for the treatment of diseases suchas hypertension, for example. The invention furthermore relates to processesfor the preparation of the compounds of the Formula(I), their use and pharmaceutical compositions comprising them.