LEE, JI MINKR,이지민,KIM, BO GYOUKR,김보규,OH, SEUNG JAKR,오승자,KIM, KYUNG AHKR,김경아,LEE, SAET BYOULKR,이샛별,HWANG, JAE WOONGKR,황재웅
申请号:
KR1020140097560
公开号:
KR1020160015076A
申请日:
2014.07.30
申请国别(地区):
KR
年份:
2016
代理人:
摘要:
Provided are: biomarker Hsp90 for predicting effects of a c-Met inhibitor a composition comprising a material to detect Hsp90 for predicting effects of a c-Met inhibitor and/or for selecting a target to apply a c-Met inhibitor a composition comprising a material to detect Hsp90 for testing effects of a c-Met inhibitor a composition comprising a Hsp90 inhibitor for reducing resistance with respect to a c-Met inhibitor and a composition comprising a c-Met inhibitor and a Hsp90 inhibitor for combined administration. The composition is capable or previously measuring an amount of Hsp90, and predicting whether to have anticancer effects of a c-Met target drug.COPYRIGHT KIPO 2016c-Met 저해제의 효능 예측을 위한 바이오마커 Hsp90, Hsp90의 검출 물질을 포함하는 c-Met 저해제의 효능 예측 및/또는 c-Met 저해제의 적용 대상 선별을 위한 조성물, Hsp90의 검출 물질을 포함하는 c-Met 저해제의 효능 검정을 위한 조성물, Hsp90 저해제를 포함하는 c-Met 저해제에 대한 저항성 저감용 조성물, 및 c-Met 저해제 및 Hsp90 저해제를 포함하는 병용 투여용 조성물이 제공된다.