PI3K protein kinase inhibitors, especially δ inhibitors and / or gamma inhibitors农业专利-农业专业知识服务系统

发明人:: BHAVAR, Prashant Kashinath,普拉尚特．卡希纳特．巴瓦,普拉尚特．卡希納特．巴瓦,VAKKALANKA, Swaroop Kumar Venkata Satya,斯瓦鲁普．库马尔．文卡塔．萨蒂亚．瓦卡拉恩卡,斯瓦魯普．庫馬爾．文卡塔．薩蒂亞．瓦卡拉恩卡,BABU, Govindarajulu,戈文达拉朱卢．巴布,戈文達拉朱盧．巴布

摘要：: The present disclosure provides novel compounds (I) that can be used as PI3K protein kinase modulators, in particular as PI3K δ and / or gamma protein kinase regulators. Methods for preparing PI3K protein kinase modulators, pharmaceutical compositions containing them, and methods of using them to treat, prevent and / or improve PI3K kinase mediated diseases or disorders are also provided.本公開提供了可用作PI3K蛋白激酶調節劑，特別是用作PI3Kδ和／或γ蛋白激酶調節劑的新型化合物(I)。本公開還提供了用於製備PI3K蛋白激酶調節劑的方法、含有它們的藥物組合物、以及使用它們治療、預防和／或改善PI3K激酶介導的疾病或病症的方法。