BOCK, Mark Gary,MOEBITZ, Henrik,PANIGRAHI, Sunil Kumar,PODDUTOORI, Ramulu,SAMAJDAR, Susanta
申请号：
TN2015000574
公开号：
TN2015000574A1
申请日:
2014.08.14
申请国别(地区):
TN
年份:
2017
代理人:
摘要：
The present invention relates to compounds of formula I in which n, R<；sub>；1 <；/sub>；, R<；sub>；2<；/sub>；,R<；sub>；3a <；/sub>；, R<；sub>；4 <；/sub>； and R<；sub>；5 <；/sub>；are defined in the Summary of the Invention； capable of inhibiting the activity of MEK. The invention further provides a process for the preparation of compounds of the invention, pharmaceutical preparations comprising such compounds and methods of using such compounds and compositions in the management of hyperproliferative diseases like cancer.
