Methods of antagonizing signal transduction in spinal cord cells using an IL-31Ra or OSMR-b antagonist

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专利权人:

ZymoGenetics; Inc.

发明人:

Yue Yao,Janine Bilsborough

申请号：

US14606063

公开号：

US09334322B2

申请日:

2015.01.27

申请国别(地区):

US

年份:

2016

代理人:

摘要：

Use of antagonists to IL-31Ra and OSMRb are used to treat inflammation and pain by inhibiting, preventing, reducing, minimizing, limiting or minimizing stimulation in neuronal tissues. Such antagonists include soluble receptors, antibodies and fragments, derivative, or variants thereof. Symptoms such as pain, tingle, sensitization, tickle associated with neuropathies are ameliorated.

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