University of Washington Through Its Center for Commercialization
发明人:
RUSSELL, David, W.
申请号:
DK12720040
公开号:
DK2699593T3
申请日:
2012.04.18
申请国别(地区):
DK
年份:
2017
代理人:
摘要:
The invention provides isolated primate cells preferably human cells that comprise a genetically engineered disruption in a beta-2 microglobulin (B2M) gene, which results in deficiency in MHC class I expression and function. Also provided are the method of using the cells for transplantation and treating a disease condition.