經取代之雜環基苯甲基吡唑及其用途农业专利-农业学术服务平台

发明人:: HAERTER, MICHAEL,海特　迈克尔,海特　邁克爾,BECK, HARTMUT,贝克　哈特穆特,貝克　哈特穆特,GRESCHAT, SUSANNE,葛雷沙特　苏珊,葛雷沙特　蘇珊,ELLINGHAUS, PETER,艾灵郝斯　彼得,艾靈郝斯　彼得,BERHOERSTER, KERSTIN,博赫斯特　克斯廷,SCHUHMACHER, JOACHIM,舒马赫　约阿希姆,舒馬,海特迈克尔,海特邁克爾,贝克哈特穆特,貝克哈特穆特,葛雷沙特苏珊,葛雷沙特蘇珊,艾灵郝斯彼得,艾靈郝斯彼得,博赫斯特克斯廷,舒马赫约阿希姆

摘要：: The present application relates to novel substituted 1-[3-(heterocyclyl)benzyl]-1H-pyrazole derivatives, to processes for preparation thereof, to use thereof for treatment and/or prevention of diseases and to use thereof for production of medicaments for treatment and/or prevention of diseases, more particularly for treatment and/or prevention of hyperproliferative and angiogenic diseases and those diseases which arise from metabolic adaptation to hypoxic states. Such treatments can be effected in the form of monotherapy or else in combination with other medicaments or further therapeutic measures.本申請案係有關一種新穎之經取代之1-[3-(雜環基)苯甲基]-1H-吡唑衍生物，其製法，其於治療及/或預防疾病上之用途，及其於製造醫藥上之用途，供治療及/或預防疾病，更具體而言，供治療及/或預防過度增生及新血管形成性疾病及因適應低氧狀態而引發之代謝疾病。此等治療法可採用單方療法或與其他醫藥或其他醫療方法組合進行。