Composition the present invention provides anti-(FXI) antibody of the new anti-factor (electricity) sense (electricity) and comprising such antibody. It combines to antibody specificity anti-fxl of the invention activated centre FXI and has contained FXI functions. The present invention also provides the anti-fxl antibody of humanization form, can be used for prevention and treatment and state, wherein pathologic thrombosis or thromboembolism are involved. The present invention also provides the anti-nucleic acid monomer fxl antibody is encoded, anti-fxl antibody is expressed in cell and method produces anti-fxl antibody.
