KARSDAL, MORTEN,HENRIKSEN, KIM,ANDREASSEN, KIM VIETZ
申请号：
CA2928654
公开号：
CA2928654A1
申请日:
2014.11.10
申请国别(地区):
CA
年份:
2015
代理人:
摘要：
Calcitonin mimetic peptides having an amino acid sequence in accordance with SEQ ID NO: 8 or SEQ ID NO: 53, each of which may be carboxylated at its N-terminal or otherwise modified to reduce the positive charge of the first amino acid and independently of that may be amidated at its C-terminal, and in each of which the 1 and 7 position cysteine residues may together be replaced by a-aminosuberic acid (Asu) are useful as medicaments for treating diabetes (Type I and/or Type II), excess bodyweight, excessive food consumption, metabolic syndrome, rheumatoid arthritis, non-alcoholic fatty liver disease, osteoporosis, or osteoarthritis, poorly regulated blood glucose levels, poorly regulated response to glucose tolerance tests, or poorly regulated of food intake.
