Methods and compositions for treating ophthalmic disease, reducing retinal neovascularization and retinal vascular leakage using progenitor cells, such as postpartum-derived cells, and conditioned media from the cells, are disclosed.所揭示者係使用前驅細胞(諸如產後衍生細胞)及來自該等細胞之條件培養基,來治療眼科疾病、減少視網膜血管新生及視網膜血管滲漏的方法及組成物。