KENNETH A. BRASEL,STEPHEN FOSTER,DOUGLAS PAT,JILIN SUN,JAMES F.,CHRISTOPHER MEHLIN
申请号:
BRPI0815368
公开号:
BRPI0815368A2
申请日:
2008.08.19
申请国别(地区):
BR
年份:
2015
代理人:
摘要:
Antigen binding proteins that bind to human c-fms protein are provided. Nucleic acids encoding the antigen binding protein, vectors, and cells encoding the same are also provided. The antigen binding proteins can inhibit binding of c-fms to CSF-I, reduce monocyte migration into tumors, and reduce the accumulation of tumor-associated macrophages.