The present disclosure is directed to the combination of a slow rate of digestion simple carbohydrate, a complex carbohydrate, a nonabsorbent carbohydrate, and an indigestible oligosaccharide for use in a method of treating a pregnant woman wherein the method results in an improvement in the health of the offspring of the pregnant woman. The disclosure is also directed to use of the combination of a slow rate of digestion simple carbohydrate, a complex carbohydrate, a nonabsorbent carbohydrate, and an indigestible oligosaccharide for the manufacture of a medicament for use in the treatment of a pregnant woman wherein the treatment results in an improvement in the health of the offspring of the pregnant woman. The improvement in the health of the offspring can be a reduction of at least one long term adverse health effect and/or an improvement in lean body mass development and formation of the offspring. The combination of carbohydrates includes a slow rate of digestion simple carbohydrate and a complex carbohydrate in combination with a non-absorbent carbohydrate and/or an indigestible carbohydrate. The carbohydrates may also be administered during lactation to further the improvement in the health of the offspring.本發明係關於用於治療妊娠婦女之方法中之含消化速率慢的簡單碳水化合物、複合碳水化合物、非吸收性碳水化合物及難消化性寡糖之組合,其中該方法可改善妊娠婦女之後代之健康。本發明亦係關於含消化速率慢的簡單碳水化合物、複合碳水化合物、非吸收性碳水化合物及難消化性寡糖之組合於製造藥劑之用途,該藥劑係用於治療妊娠婦女,其中該治療可改善妊娠婦女後代健康。後代健康之改善可為減少至少一種長期不利健康效應及/或改善後代之精瘦體質發展及形成。該碳水化合物之組合包含消化速率慢的簡單碳水化合物及複合碳水化合物與非吸收性碳水化合物及/或難消化性碳水化合物。亦可在哺乳期間投與該等碳水化合物,以進一步改善該後代健康。