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Methods to inhibit intracellular growth of bacteria and to treat bacteria-mediated diseases
专利权人:
发明人:
Amit Singhal,Gennaro De Libero
申请号:
US14426659
公开号:
US09539222B2
申请日:
2013.09.04
申请国别(地区):
US
年份:
2017
代理人:
摘要:
Disclosed is a method of preventing, treating or inhibiting bacterial infections. The method comprises administering at least one of the compounds disclosed herein. Also disclosed are methods of increasing acidity of bacterial phagosomes to inhibit bacterial growth, methods of increasing mitochondrial reactive oxygen species (mROS) generation to inhibit bacterial growth in a cell, pharmaceutical compositions and uses thereof.
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