JUN HELEN TONI,KEHRY MARILYN,BOWERS PETER,KING DAVID J
申请号:
IN201717028820
公开号:
IN201717028820A
申请日:
2017.08.14
申请国别(地区):
IN
年份:
2017
代理人:
摘要:
The invention relates to an isolated immunoglobulin heavy chain polypeptide and an isolated immunoglobulin light chain polypeptide that bind to a protein encoded by the Lymphocyte Activation Gene 3 (LAG 3). The invention provides a LAG 3 binding agent that comprises the aforementioned immunoglobulin heavy chain polypeptide and immunoglobulin light chain polypeptide. The invention also provides related vectors compositions and methods of using the LAG 3 binding agent to treat a disorder or disease that is responsive to LAG 3 inhibition such as cancer or an infectious disease.