Adam R. Renslo,Erica M.W. Lauterwasser,Shaun D. Fontaine,Benjamin B. Spangler,James A. Wells
申请号:
US16364577
公开号:
US20190284224A1
申请日:
2019.03.26
申请国别(地区):
US
年份:
2019
代理人:
摘要:
Disclosed herein, inter alia, are prodrug compositions and methods of using the same for treatment and detection of disease. Specifically, disclosed herein is a compound of formula (I) having spiro-fused 1,2,4-trioxolane and piperidine rings, namely, 1,2,4-trioxa-8-azaspiro[4.5]decane. Also disclosed is a pharmaceutical composition containing the compound and a pharmaceutically acceptable carrier.