Disclosed is a composition comprising an extract of alpine wormwood ( Artemisia umbelliformis ) as an active ingredient. The composition disclosed in the present specification, which comprises the extract of alpine wormwood ( Artemisia umbelliformis ), exhibits an effect of reducing the amount of endothelin 1 and reducing the overexpression of NK1 R and EDN1 genes. Accordingly, due to such effects, the alpine wormwood ( Artemisia umbelliformis ) extract of the present disclosure can exhibit benefits for maintaining skin homeostasis as well as an anti-stress effect, and thus can be widely used in pharmaceutical or cosmetic fields as a composition for maintaining skin homeostasis.