HETTWER STEFAN,KUCSERA STEFAN,VRIJBLOED JAN WILLEM
申请号:
NZ59785310
公开号:
NZ597853A
申请日:
2010.09.01
申请国别(地区):
NZ
年份:
2014
代理人:
摘要:
597853 Disclosed is a modified agrin fragment having in vivo activity for use as medicament, the fragment comprising at least the domains LG2 and LG3 of human or mouse agrin in a covalently interlinked form, and modified in such a way that the fragment cannot be cleaved by neurotrypsin, wherein the modified agrin fragment is not C44y0z0K/A.