OHAGAN, Derek,BAUDNER, Barbara,SKIBINSKI, David A.G.,SINGH, Manmohan
申请号:
EP12709382
公开号:
EP2680885B8
申请日:
2012.03.02
申请国别(地区):
EP
年份:
2018
代理人:
摘要:
Combination vaccine compositions as well as methods for their manufacture have a relatively low amount of antigen and/or a relatively low amount of aluminium, but they can nevertheless have immunogenicity which is comparable to combination vaccines with a relatively high amount of antigen and/or a relatively high amount of aluminium. Aluminium-free combination vaccine compositions are also provided e.g. compositions which are adjuvanted with an oil-in-water emulsion adjuvant.