POMPER, MARTIN GILBERT,MEASE, RONNIE CHARLES,CHEN, YING
申请号:
CA2732632
公开号:
CA2732632C
申请日:
2009.07.31
申请国别(地区):
CA
年份:
2018
代理人:
摘要:
Prostate-specific membrane antigen (PSMA) bindingcompounds having radioisotope substituents are described, as well aschemical precursors thereof. Compounds include pyridine containingcompounds, compounds having phenylhydrazine structures, and acylatedlysine compounds. The compounds allow ready incorporation of radionuclidesfor single photon emission computed tomography (SPECT)and positron emission tomography (PET) for imaging, for example,prostate cancer cells and angiogenesis.