Byeong Cheol Ahn,Jae Tae Lee,Je Yeol Cho,Jung Soo Yu,Yong Jin Lee,Sang Woo Lee,You La Lee
申请号：
US12704877
公开号：
US08388937B2
申请日:
2010.02.12
申请国别(地区):
US
年份:
2013
代理人:
摘要：
A specific targeting peptide binding to glypican-3 can specifically binds to glypican-3 overexpressed in carcinoma cells and includes an amino acid sequence represented by SEQ ID NO:1 or some thereof. Glypican-3 is overexpressed in malignant tumors including hepatocellular carcinoma, melanoma, germ cell tumor, etc., and may be targeted in diagnosis and treatment of tumors by labeling the targeting peptide. A diagnosis using the specific peptide may detect even small tumors more accurately than conventional methods. A treatment method using the specific peptide may remove only carcinoma cells without harming other normal tissues.
