University of Virginia Patent Foundation; d/b/a Un
发明人:
Brent A. FRENCH,Brian H. ANNEX
申请号:
US13673351
公开号:
US20130136729A1
申请日:
2012.11.09
申请国别(地区):
US
年份:
2013
代理人:
摘要:
The present application discloses compositions and methods useful for targeting and treating injured or diseased muscle, including cardiac and skeletal muscle. Disclosed herein are adenoviral vectors modified to contain enhancers, promoters, and genes to target muscle with high efficiency and to induce tissue specific gene expression of transgenes.