Provided herein are (8S, 9R)-5-fluoro-8-(4-fluorophenyl)-9-(1-methyl-lH-1,2,4-triazol-5- yl)-8,9-dihydro-2H-pyrido[4,3,2-de]phthalazin-3(7H)-one tosylate salt forms, including crystalline forms, and methods of their preparation. Pharmaceutical compositions comprising a (8S,9R)-5-fiuoro-8-(4-fluorophenyl)-9-(1-methyl-1H-1,2,4-triazol-5-yl)-8,9-dihydro-2H- pyrido[4,3,2-de]phthalazin-3(7H)-one tosylate salt are also provided, as are methods of using (8S,9R)-5-fluoro-8-(4-fluorophenyl)-9-(1-methyl-1H-1,2,4-triazol-5-yl)-8,9-dihydro-2H- pyrido[4,3,2-de]phthalazin-3(7H)-one tosylate salt to treat a disease or condition, such as a cancer.La présente invention concerne des formes du sel tosylate de la (8S, 9R)-5-fluoro-8-(4-fluorophényl)-9-(1-méthyl-lH-1,2,4-triazol-5- yl)-8,9-dihydro-2H-pyrido[4,3,2-de]phtalazin-3(7H)-one, y compris des formes cristallines et leurs procédés de préparation. Linvention concerne également des compositions pharmaceutiques contenant un sel tosylate de la (8S,9R)-5-fluoro-8-(4-fluorophényl)-9-(1-methyl-1H-1,2,4-triazol-5-yl)- 8,9-dihydro-2H- pyrido[4,3,2-de]phtalazin-3(7H)-one ainsi que des méthodes dutilisation du sel tosylate de la (8S,9R)-5-fluoro-8-(4-fluorophényl)-9- (1-méthyl-1H-1,2,4-triazol-5-yl)-8,9-dihydro-2H- pyrido[4,3,2-de]phtalazin-3(7H)-one pour traiter une maladie ou une affection, telle quun cancer.
