method of reducing side effects and method of enhancing the effect of an immunomodulator administered to a subject in need thereof; methods for treating disease associated with overactivation of monocytes to activated macrophages, type II diabetes or related complications, disease associated with migration of activated monocytes or macrophages, disease associated with overproduction of scd14 and / or scd163 by activated macrophages; sodium chloride compound; pharmaceutical composition; method for diagnosing a macrophage-related disease in a subject; and method for determining the effectiveness
Neuraltus Pharmaceuticals, INC.;The Regents of the University of California
发明人:
ARASTEH ARI AZHIR,MICHAEL S. MCGRATH
申请号:
BR112012002333
公开号:
BR112012002333A2
申请日:
2010.07.23
申请国别(地区):
BR
年份:
2017
代理人:
摘要:
The present invention provides a method of treating a macrophage related disease comprising administering to a subject in need thereof an effective amount of an oxidative agent or an immunosuppressive agent. The present invention also provides a method of modulating macrophage accumulation or activation comprising administering to a subject in need thereof an effective amount of an oxidative agent or an immunosuppressive agent. The oxidative agent can be chlorite or a chlorite containing compound.