Joost Henric Nicolaas Schuitemaker,Thomas Ivo Franciscus Hubert Cremers
申请号：
US15559299
公开号：
US20180059122A1
申请日:
2016.03.21
申请国别(地区):
US
年份:
2018
代理人:
摘要：
The present invention relates to methods of typing a female subject as being at risk of developing gestational diabetes, comprising determining a level of expression of Secreted Frizzled-Related Protein 4 (sFRP4). The invention further relates to methods of treating of a subject being at risk of developing, gestational diabetes, comprising typing the subject according to the methods of the invention, and treating the subject with a dietary meal plan and/or physical activity. The invention additionally relates to kit for a pregnant female subject for susceptibility to gestational diabetes, use of a kit according to the invention for typing a female subject as being at risk of developing gestational diabetes, and to an antibody specific to sFRP4 for use in a method for determining a risk of a female subject of developing gestational diabetes.
