LONDON, TIMOTHY,PATAKAS, AGAPITOS,HANNIGAN, ADELE,COSIMO, EMILIO,COYLE, NANCY,SCOTT, ANGELA,LEEK, MICHAEL
申请号：
CA3044801
公开号：
CA3044801A1
申请日:
2018.01.26
申请国别(地区):
CA
年份:
2018
代理人:
摘要：
A modified T cell is described which is adapted to overexpress SLC1A5, an isoform of SLC1A5 or an alternative tryptophan or glutamine transporter. Further described is the use of such modified T cells in the treatment of disease, in particular cancer, methods to select modified T cells which overexpress SLC1A5 and nucleic acids and vectors to provide for such modified T cells.
