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SUSTAINED RELEASE ORAL MATRIX AND METHODS OF MAKING THEREOF
专利权人:
Gaurav Thakersi Tolia
发明人:
Gaurav Thakersi Tolia
申请号:
US13190398
公开号:
US20130028955A1
申请日:
2011.07.25
申请国别(地区):
US
年份:
2013
代理人:
摘要:
A solid dosage form suitable for forming a tablet for the containment and delivery of medicament is provided wherein the matrix forming material is a pressure sensitive adhesive, present in the amount from about 0.1 to about 40 weight %, based on the total weight of the composition. The dosage form is comprised of the medicament and a water-insoluble polymer silicone pressure sensitive adhesive and allows release of the medicament in a controlled fashion depending on simple parameters such as weight percent of the polymer silicone adhesive. A sustained release dosage form is provided for delivery of medicament wherein the release rate of medicament does not depend on the dissolution medium of the pH. Another aspect of invention is formation of solid tablets of poorly compressible material and the method for making the solid composition. The dosage form for this invention s particularly suitable for oral dosage forms.
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中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/
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