Patrick Vlieghe;Michel Khrestchatisky;Marion David;Yves Molino
发明人:
Michel Khrestchatisky,Marion David,Yves Molino,Patrick Vlieghe
申请号：
US13125634
公开号：
US08729029B2
申请日:
2009.10.20
申请国别(地区):
US
年份:
2014
代理人:
摘要：
The invention relates to peptide derivatives (peptides and pseudo-peptides) and use thereof as vectors for molecules of interest. The invention also relates to conjugates containing a peptide derivative of the invention bound to a molecule of interest. The peptides and prodrug conjugates of the invention can be used to vectorise molecules of pharmaceutical or diagnostic interest, such as, for example, therapeutic molecules, imaging or diagnostic agents, or molecular probes, across cell membranes, and notably to promote their transport across the blood-brain barrier (BBB).
