The present invention provides a set of large-scale and high-efficiency fly maggot culture equipment and a large-scale and high-efficiency fly maggot culture process and pertains to fly maggot culture. The equipment comprises at least one culturing workshop with a multi-functional ceiling. At least one feeder traveling along double-row burden distributing rails is arranged in the culturing workshop. A pair of main rails is perpendicularly arranged on the front of one ends of the burden distributing rails. A rail car used for transferring the feeder among different burden distributing rails is arranged on the main rails. Transferring rails horizontally perpendicular to the main rails are arranged on the rails car. The height of the transferring rails is consistent with the height of the distributing rails. The workshop ground between the two rails of the distributing rails form a culturing bed for fly maggot culture. The equipment also includes a central control apparatus connected with an alarm and a fly maggot separator. The equipment and the process provided in this present invention can realize incessant fly maggot flow line culture, without being affected by temperature, and is much highly automatic to realize fly maggot production in large scale and with high effectiveness.