A loading unit configured for engagement with a surgical instrument isdisclosed.The loading unit comprises a proximal body portion and a tool assembly. Theproximalbody portion defines a longitudinal axis. The tool assembly is disposed inmechanicalcooperation with the proximal body portion and includes a cartridge assemblyand ananvil assembly. At least one of the cartridge assembly and the anvil assemblyis movablewith respect to the other between an open position and an approximatedposition toengage tissue therebetween. The cartridge assembly is configured to house aplurality offasteners therein. The diameter of the tool assembly is less than or equal toabout 8 mm.