Disclosed are nutritional compositions including human milk oligosaccharides and nucleotides that can be administered to preterm infants, term infants, toddlers, and children for reducing inflammation and the incidence of inflammatory diseases.本發明揭示包括人乳寡醣及核苷酸之營養組合物,其可投與早產兒、足月兒、幼兒及孩童以減少發炎及發炎疾病之發生率。