Methods of Identifying and Treating Patient Populations Amenable to Cancer Immunotherapy

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专利权人:

The Regents of the University of California

发明人:

Matthew Spitzer,Lawrence Fong

申请号：

US16479211

公开号：

US20190378594A1

申请日:

2018.01.19

申请国别(地区):

US

年份:

2019

代理人:

摘要：

Methods for identifying cancer patients amenable to anti-cancer immunotherapy are provided along with methods of monitoring cancer therapy. Also provided are methods of treating cancer patients amenable to anti-cancer immunotherapy. The methods involve determining the level of CD127<；low>；PD-1<；low>；T cells. The patients are treated with an immune checkpoint inhibitor, such as an anti-CTLA-4 antibody, e.g. ipilimumab.

来源网站：

中国工程科技知识中心

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http://www.ckcest.cn/home/