A non-gelatin encapsulation system for liquid filled soft capsules, by nature of the carrier, the cationic-ionic balance of the carrier and the active ingredients, or the concentration of the active ingredients and excipients, are difficult or impossible to commercially encapsulate in gelatin capsules. In particular, the system is adapted for the encapsulation of highly basic, or alkaline, fills. The system provides for a predominantly starch and gelling carrageenan based shell, which displays high resistance to both concentrated fills and to alkaline fills, in particular, to those fills which contain the salt or salts of weak acids and strong bases.使用於液體填充軟膠囊之非明膠囊封系統,由於載劑之性質、載劑和活性成分之陽離子平衡,或活性成分和賦形劑之濃度,因此有困難或不可能商業化地囊封於明膠膠囊中。特定而言,本系統係用於高鹼性或鹼質填充物之膠囊製造。本系統提供主要以澱粉和凝膠化角叉菜膠(carrageenan)為底之殼,其對於濃縮填充物和鹼質填充物兩者,特定而言為對於含有弱酸和強鹼鹽類或該等鹽類之填充物,皆表現出高抗性。