作為CCR9拮抗劑的吡唑-1-基苯磺酰胺

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专利权人:

INC.;CHEMOCENTRYX

发明人:

CHEN, Xi,FAN, Junfa,FAN, Pingchen,KRASINSKI, Antoni,LI, Lianfa,LUI, Rebecca, M.,McMAHON, Jeffrey, P.,POWERS, Jay, P.,ZENG, Yibin,ZHANG, Penglie

申请号：

HK18105070.2

公开号：

HK1245773A

申请日:

2018.04.19

申请国别(地区):

HK

年份:

2018

代理人:

摘要：

Compounds of formula (II) are provided that act as potent antagonists of the CCR(9) receptor. Animal testing demonstrates that these compounds are useful for treating inflammation, a hallmark disease for CCR(9). The compounds are generally aryl sulfonamide derivatives and are useful in pharmaceutical compositions, methods for the treatment of CCR(9)-mediated diseases, and as controls in assays for the identification of CCR(9) antagonists.

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中国工程科技知识中心

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http://www.ckcest.cn/home/