Jon Florholmen,Trine Olsen,Renathe Rismo,Rasmus Goll,Guanglin Cui
申请号:
US14653750
公开号:
US10012654B2
申请日:
2013.12.23
申请国别(地区):
US
年份:
2018
代理人:
摘要:
The present invention provides a method of determining whether a patient with inflammatory bowel disease (IBD) and who has been treated with anti TNFα therapy is in immunological remission (IR), said method comprising determining the level of a cytokine selected from TNFα, IL-17 and IFN-y in a Gl mucosal sample from said patient. Also provided are methods of prognosis and treatment using said method of determination, in particular discontinuing treatment if said patient is in IR and continuing treatment if said patient is not in IR.