David Owen Bates;Steven James Harper;Andrew Salmon
发明人:
David Owen Bates,Steven James Harper,Andrew Salmon
申请号：
US13113643
公开号：
US20120010138A1
申请日:
2011.05.23
申请国别(地区):
US
年份:
2012
代理人:
摘要：
The invention provides VEGFxxxb, or an agent which selectively promotes the expression of VEGFxxxb in preference to VEGFxxx in cells of a subject or in vitro, or an expression vector system which causes the expression of the VEGFxxxb in a host organism, for use in treating or preventing microvascular hyperpermeability disorders, or in regulating the pro-angiogenic pro-permeability properties of VEGFxxx isoforms, or in supporting epithelial cell survival without increased permeability, or in reducing the nature (for example the number density and/or size) of fenestrations of epithelial filtration membranes in vivo or in vitro.
