Danielle L. Aubele;Jennifer Sealy;John P.;Robert A. Galemmo, JR.;Anh P. Truong; JR.;Yong-Liang Zhu;Roy K. Hom;Robert A. Galemmo;R. Jeffrey Neitz;Marc Adler;Simeon Bowers;Paul Beroza;Dean Richard Artis, I;Xiaocong Michael Ye
发明人:
Robert A. Galemmo, JR.,Dean Richard Artis, I,Xiaocong Michael Ye,Danielle L. Aubele,Anh P. Truong,Simeon Bowers,Roy K. Hom,Yong-Liang Zhu,R. Jeffrey Neitz,Jennifer Sealy,Marc Adler,Paul Beroza,John P.
申请号:
US13267834
公开号:
US20120115848A1
申请日:
2011.10.06
申请国别(地区):
US
年份:
2012
代理人:
摘要:
The present invention provides compounds having a structure according to Formula (I):or a salt or solvate thereof, wherein ring A, U1, U2, U3, R2, R3 and R4 are defined herein. The invention further provides pharmaceutical compositions including the compounds of the invention and methods of making and using the compounds and compositions of the invention, e.g., in the treatment and prevention of various disorders, such as Parkinson's disease.