SMITH-SWINTOSKY, VIRGINIA L.,史密斯,史密斯,REITZ, ALLEN B.,瑞特兹,瑞特茲
申请号:
TW095147364
公开号:
TWI435722B
申请日:
2006.12.18
申请国别(地区):
TW
年份:
2014
代理人:
摘要:
The present invention relates to a use of one or more novel benzo-fused heterocycle sulfamide derivatives of formula (I) and formula (II) as herein defined for the manufacture of a medicament for neuroprotection, for treating an acute neurodegenerative disorder, for treating a chronic neurodegenerative disorder and / or for preventing neuron death or damage following brain, head and / or spinal cord trauma or injury.本發明有關於一種或多種具有如此處所定義之化學式(I)以及化學式(Π)的新穎苯并-稠合雜環磺醯胺衍生物,它們於神經保護、於治療一急性神經退化疾病、於治療一慢性神經退化疾病之一醫藥物製造及/或在腦、頭部和/或脊髓創傷或受損後防止神經元死亡或受損的用途。