the invention generally relates to \u0438\u043c\u043c\u0443\u043d\u043e\u0433\u0435\u043d\u043d\u044b\u043c combinations containing at least five antigens from species of genus \u043c\u0438\u043a\u043e\u0431\u0430\u043a\u0442\u0435\u0440\u0438\u0439, as well as to their \u0433\u0438\u0431\u0440\u0438\u0434\u0430\u043c and molecules nucleic acid \u043a\u043e\u0434\u0438\u0440\u0443\u044e\u0449\u0438\u043c such combined antigen and hybrids.the invention also relates to nucleic acid molecules, cells \u0432\u0435\u043a\u0442\u043e\u0440\u0430\u043c, masters and \u043a\u043e\u043c\u043f\u043e\u0437\u0446\u0438\u044f\u043c containing or \u043a\u043e\u0434\u0438\u0440\u0443\u044e\u0449\u0438\u043c the combination \u043c\u0438\u043a\u043e\u0431\u0430\u043a\u0442\u0435\u0440 \u0438\u0430\u043b\u044c\u043d\u044b\u0445 antigens and \u0441\u043b\u0438\u0442\u044b\u0435 \u043f\u043e\u043b\u0438\u043f\u0435\u043f\u0442\u0438\u0434\u044b, as well as to how their \u0440\u0435\u043a\u043e\u043c\u0431\u0438\u043d\u0430\u043d\u0442\u043d\u043e\u0439 products.the invention also relates to methods of use of such combinations \u043c\u0438\u043a\u043e\u0431\u0430\u043a\u0442\u0435\u0440\u0438\u0430\u043b\u044c\u043d\u044b\u0445 reports antigens, polypeptides, vectors, host cells, compositions, specifically, for \u0438\u043d\u0434\u0443\u0446\u0438\u0440\u043e\u0432\u0430\u043d\u0438\u044f or stimulating the immune response against infection \u043c\u0438\u043a\u043e\u0431\u0430\u043a\u0442\u0435\u0440\u0438\u0435\u0439 or any disease caused by or associated with \u0438\u043d\u0444\u0435\u043a\u0446 it \u043c\u0438\u043a\u043e\u0431\u0430\u043a\u0442\u0435\u0440\u0438\u0435\u0439.the invention also relates to antibodies directed to the antigen and \u043c\u0438\u043a\u043e\u0431\u0430\u043a\u0442\u0435\u0440\u0438\u0430\u043b\u044c\u043d\u044b\u0435 \u0441\u043b\u0438\u0442\u044b\u0435 \u043f\u043e\u043b\u0438\u043f\u0435\u043f\u0442\u0438\u0434\u044b, which can be used in the diagnosis of i
