Disclosed herein are novel compounds and uses thereof. The present compounds may suppress the activity of farnesyl transferase and thus, may act as modulators of immune cells therefor, they are useful for the development of a medicament for treating diseases that are associated with or caused by excessive levels of farnesyl transferase or immune response. Also disclosed herein are pharmaceutical compositions containing the present compounds.本揭示內容是關於新穎的化合物及其用途。本發明化合物具有抑制法尼基轉移酶活性的功效,因此可作為免疫細胞的調控劑;據此,該些化合物可用以製備一藥物,以治療與過量表現法尼基轉移酶或免疫反應相關或所引發的疾病。本揭示內容亦提供包含本發明化合物之藥學組合物。